Bioanalytical Chemist, Biotechnology Research and Development, Mass Spectrometry Expert Consultant Resume
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Resume of LQO, Ph.D. Consultant
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  • Biotechnology Research
  • Pharmaceutical
  • Environmental Chemistry Research

 

This expert attended the Texas A&M University in College Station, TX for doctoral studies and earned a Ph.D. in Evaluation of Polyatomic Primary Ions for Organic Secondary Ion Mass Spectrometry from that university.

This expert attended the University of North Texas in Denton, TX and earned a B.S. from that university.

 

Bioanalytical Chemist, Biotechnology Research and Development, Mass Spectrometry Expert Consultant Resume
 

This expert specializes in bioanalytical chemistry, biotechnology research in the development of novel protein binding agents, and surface Plasmon resonance (SPR). This expert has extensive knowledge in HPLC and in the use of mass spectrometry in surface science, environmental water analysis, and proteomics.

This expert has over 10 years of experience in mass spectrometry design, service, and operation in a variety of industries utilizing secondary ion mass spectrometry (SIMS), GC-MS, LC-MS, and MALDI.

This consultant also specializes in new technology development including SIMS instrument design and construction, vacuum system design and construction, microarray design and development, and high throughput screening (HTS) development. This expert also has experience in the design and synthesis of bivalent protein binding ligands.

This expert has managed a project in the development of protein binding ligands and has successfully integrated a wide variety of analytical technologies necessary for the discovery and characterization of these ligands. These technologies include ligand discovery tools that utilize HTS by SPR and by peptide microarrays; ligand characterization using binding assays that employ label-free sensing using SPR and resonant waveguide (RWG) technology, fluorescent polarization (FP), ELISA, equilibrium dialysis, and protein-peptide cross-linking.

This expert has successfully evaluated and performed due-diligence on a wide variety of analytical platforms for major instrumentation purchasing, and has successfully developed and managed collaborative research projects across departments, institutions, and companies.

 

Consultant, Kevin Kennedy Associates Inc.

Providing expertise in bioanalytical chemistry, biotechnology research and development, mass spectrometry, and related expertise to a wide variety of clients.

 

Assistant Research Professor, The Biodesign Institute at Arizona State University, Tempe, AZ

Organized, designed, and coordinated all aspects of complex multi-investigator research project in high throughput (HT) screening of peptide libraries, chemically synthesizing bivalent ligands, and developing the analytical methodology to screen and characterize lead compounds. Research led to 1 patent awarded and 2 research grants funded. Advised and contributed to operations that led to the expansion of research center from 8 to 70 people in 3 years. Responsible for purchase, installation, and operation of over $2M of analytical instrumentation including mass spectrometers, SPR systems, and HPLC systems. Established and developed process that produced 5,000 peptide microarrays in 2 years. Oversaw purchase, installation, and operation of Biacore A-100 SPR system, one of the first systems installed in an American university. Consulted small biotechnology start-up in the modification and improvement of a portable SPR device. Developed protocols and data analysis methods that enabled the HT screening of 10,000 peptides against 4 proteins by the A-100, which is the largest library screened with this instrument to date. Participated in collaboration with Corning Life Sciences in applications development for the Corning EPIC high throughput label-free detection system. Oversaw purchase, installation and operation of Agilent HPLC-Chip and XCT Ultra Ion Trap, one of the first HPLC-Chip systems installed in an American university. Developed mass spectrometry methods and protocols for antigen discovery in cancer vaccine research program. Trained and mentored high school, undergraduate, graduate students, and post-doctoral research fellows.

 

Assistant Research Professor, UT Southwestern Medical Center, Dallas, TX

Managed mass spectrometry facility in Center for Biomedical Invention, which included an Applied Biosystems MALDI-TOF and an MDS Sciex QStar XL. Conducted research in the identification of unknown proteins cross-linked to a target protein. Organized and coordinated move of research operations to The Biodesign Institute at Arizona State University.

 

Post-Doctoral Fellow, U.S. Environmental Protection Agency (EPA), Cincinnati, OH

Developed LC-TOF-MS methods for the detection of known and unknown algal toxins listed on the Candidate Contaminant List. Developed and coordinated a collaboration between EPA and Thermo Finnigan to apply high resolution, high mass accuracy mass spectrometry using the LTQ-FT for water analysis, assisting in development of new market for the product. Published review article on the use of high mass accuracy MS instrumentation in water analysis. Discovered new algal toxins from cyanobacteria and published findings in Analytical Chemistry.

 

Technical Support Specialist, Waters Corporation, Beverly, MA

Trained in operation, maintenance and service of Waters LC-MS systems, and Micromass TOF mass spectrometers, including component-level electronics and ion optics repairs. Responsible for customer support involving troubleshooting instrument and application problems as well as evaluating and directing the appropriate service response to minimize customer disruption. Led customer liaison on GCT, GC-MS system, identifying customer hardware, software, or application issues and coordinating service and support between US and UK service organizations to quickly solve customer problems. Participated in customer escalations to resolve escalated service problems that could result in loss of service contracts or new instrument sales.

 

Research Assistant, Texas A&M University, College Station, TX

Designed and built vacuum system to house a new SIMS instrument equipped with a gold liquid metal ion source. Designed and built primary ion sources that used polyatomic primary ions including: SF5+, C60+, and cesium iodide clusters. Used polyatomic primary ions to explore the fundamentals of the ion-solid collision process on polymer and self-assembled monolayer surfaces. Participated in a collaborative project with the Physics Department at the California Institute of Technology in a study of ion backscattering. Participated in a collaborative research project that used SIMS to examine the spatial distribution of lipids within a lipid bilayer.

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